Mad About You has garnered critical praise for its realistic portrayal of marriage and the chemistry between Reiser and Hunt. Gold's version is available on the collection Thank You for Being a Friend: The Best of Andrew Gold.
Baker's version was used on several episodes of the last two seasons, in addition to Gold's version, and appears on the show's soundtrack album. The theme was originally performed by Andrew Gold, but a version performed by Anita Baker made its debut at the beginning of the sixth season. The show's theme song, 'Final Frontier', was composed by Reiser and Don Was. However, ratings fell sharply that year as the series was shuffled away from its Tuesday slot to prop up a fledgling Monday night line-up of comedies on NBC. Helen Hunt and Paul Reiser were paid $1 million per episode for the last season (with their contracts calling for them to be paid equally). Near the end of the show's run, they have a baby daughter, whom they name Mabel.
The series focuses mainly on newlyweds Paul Buchman, a documentary filmmaker, and Jamie Stemple Buchman, a public relations specialist, as they deal with everything from humorous daily minutiae to major struggles.